USE OF IONIC MATRICES FOR MALDI MASS SPECTROMETRY ANALYSIS OF TISSUE SECTIONS

R. Lemaire (1) , I. Fournier (1) , M. Salzet (1) , Jc. Tabet (2)

1 NA - Neuroimmunologie des annélides
2 SSFMB - Synthèse, Structure et Fonction de Molécules Bioactives

The invention concerns improved methods for studying peptides/proteins expression in a tissue section or for determining at least one compound, in particular a protein, expression map in a tissue section, using ionic MALDI matrices.

Mots clés: MALDI imaging; Mass spectrometry; Ionic matrices

Domaines: Biochimie, Biologie Moléculaire; Ingénierie biomédicale; Cancer; Chimie analytique

R. Lemaire, I. Fournier, M. Salzet, Jc. Tabet. USE OF IONIC MATRICES FOR MALDI MASS SPECTROMETRY ANALYSIS OF TISSUE SECTIONS. United States, Patent n° : WO2006IB02311 20060607. 2007, pp.43. ⟨hal-00167309⟩