Skip to Main content Skip to Navigation
Journal articles

Mutations in the eIF(iso)4G translation initiation factor confer high resistance of rice to Rice yellow mottle virus.

Abstract : We report here evidence of the role that the isoform of the eukaryotic translation initiation factor 4G (eIF(iso)4G) plays in naturally occurring resistance in plant/virus interactions. A genetic and physical mapping approach was developed to isolate the Rymv1 locus controlling the high recessive resistance to Rice yellow mottle virus (RYMV) in the rice (Oryza sativa) variety Gigante. The locus was mapped to a 160-kb interval containing a gene from the eIF(iso)4G family. The stable transformation of a resistant line with the cDNA of this gene, derived from a susceptible variety, resulted in the loss of resistance in transgenic plants. The allelic variability of this gene was analysed in three resistant and 17 susceptible varieties from different cultivated rice species or subspecies. Compared with susceptible varieties, resistant varieties present specific alleles, characterized by either amino acid substitutions or short amino-acid deletions in the middle domain of the protein. The structure of this domain was modelled and showed that the substitutions were clustered on a small surface patch. This suggests that this domain may be involved in an interaction with the virus.
Document type :
Journal articles
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-00164214
Contributor : Elisabeth Goetschy <>
Submitted on : Thursday, July 19, 2007 - 4:25:28 PM
Last modification on : Tuesday, August 27, 2019 - 9:20:05 AM

Links full text

Identifiers

Collections

Citation

Laurence Albar, Martine Bangratz-Reyser, Eugénie Hébrard, Marie-Noëlle Ndjiondjop, Monty Jones, et al.. Mutations in the eIF(iso)4G translation initiation factor confer high resistance of rice to Rice yellow mottle virus.. Plant Journal, Wiley, 2006, 47 (3), pp.417-26. ⟨10.1111/j.1365-313X.2006.02792.x⟩. ⟨hal-00164214⟩

Share

Metrics

Record views

191