Chiral induction in quinoline-derived oligoamide foldamers: assignment of helical handedness and role of steric effects

Christel Dolain (1) , Hua Jiang (1) , Jean-Michel Léger (2) , Philippe Guionneau (3) , Ivan Huc (1)

1 Chimie supramoléculaire biomimétique et bio-organique - Institut Européen de Chimie et Biologie
2 Laboratoire de Pharmacochimie
3 ICMCB - Institut de Chimie de la Matière Condensée de Bordeaux

Chiral groups attached to the end of quinoline-derived oligoamide foldamers give rise to chiral helical induction in solution...

Mots clés: Aromatic delta-peptides; Secondary structure; Absolute configuration; Beta-peptides; Screw sense; N'-linked oligoureas; Optical properties; X-ray diffraction; Acid oligomers; Alpha-helix; Amino-acids

Domaines: Matériaux

Christel Dolain, Hua Jiang, Jean-Michel Léger, Philippe Guionneau, Ivan Huc. Chiral induction in quinoline-derived oligoamide foldamers: assignment of helical handedness and role of steric effects. Journal of the American Chemical Society, 2005, 127 (37), pp.12943-12951. ⟨10.1021/ja0527828⟩. ⟨hal-00096047⟩