Impact of Medicine Withdrawal on Reporting of Adverse Events Involving Therapeutic Alternatives: A Study from the French Spontaneous Reporting Database

Cécile Pageot (1) , Julien Bezin (2) , Andy Smith (3, 4) , Mickael Arnaud , Francesco Salvo (5) , Françoise Haramburu (6) , Antoine Pariente (7) , Bernard Bégaud (8)

1 UB - Université de Bordeaux
2 BPH - Bordeaux population health
3 CED - Centre Émile Durkheim
4 Fondation Nationale des Sciences Politiques [FNSP]
5 Food and Environmental Science
6 Département de Pharmacologie
7 INSERM U1219 - UB - ISPED - Team MORPH3EUS
8 Pharmacoepidemiologie et évaluation de l'impact des produits de santé sur les populations

The objective of this study was to analyse the changes in the reporting of adverse events (AEs) for therapeutic alternatives after the withdrawal of three medicines (dextropropoxyphene, pioglitazone and tetrazepam) from the market for safety reasons.

Mots clés: medicine; therapeutic alternatives; politics

Domaines: Science politique; Sociologie

Cécile Pageot, Julien Bezin, Andy Smith, Mickael Arnaud, Francesco Salvo, et al.. Impact of Medicine Withdrawal on Reporting of Adverse Events Involving Therapeutic Alternatives: A Study from the French Spontaneous Reporting Database. Drug Safety, 2017, 40 (11), pp.1099-1107. ⟨10.1007/s40264-017-0561-y⟩. ⟨hal-01629228⟩