Search a new core materials for magnetic fluid hyperthermia : preliminary chemical and physical issues

Emil Pollert (1) , Pavel Veverka (1) , Miroslav Veverka (1) , Ondřej Kaman (1, 2) , Karel Závěta (1) , Sébastien Vasseur (3) , Romain Epherre (3) , Graziella Goglio (3) , Etienne Duguet (3)

1 Institute of Physics
2 Department of Cell Biology
3 ICMCB - Institut de Chimie de la Matière Condensée de Bordeaux

Today the use of nanoparticles based on magnetite Fe3O4 or maghemite γ-Fe2O3 for magnetic fluid hyperthermia (MFH) application is preferred for evident reasons as biocompatibility and easy synthesis. However, they only show moderate heating capacities because their magnetic properties cannot be simply adjusted to a suitable level. A possible improvement of the MFH technique consists in using more complex magnetic oxides such as: (i) cobalt ferrite and derived phases whose magnetic properties depend on the composition and coercivity is essentially controlled by the magnetocrystalline and/or shape anisotropy, (ii) La1−xSrxMnO3 perovskites whose magnetic properties are influenced by the composition and crystallite size, and (iii) SrFe12O19/γ-Fe2O3 composites whose magnetic properties are mainly controlled by the ratio of the respective magnetic phases. Our main results concerning the synthesis of these compounds in the form of submicronic particles, their magnetic properties and their heating abilities are summarized, compared and discussed in this paper.

Mots clés: Magnetic nanoparticles; Magnetic fluid hyperthermia; Cobalt ferrite; Manganese perovskites; Sr-hexaferrite/maghemite composites

Domaines: Matériaux

Emil Pollert, Pavel Veverka, Miroslav Veverka, Ondřej Kaman, Karel Závěta, et al.. Search a new core materials for magnetic fluid hyperthermia : preliminary chemical and physical issues. Progress in Solid State Chemistry, 2009, 37 (1), pp.1-14. ⟨10.1016/j.progsolidstchem.2009.02.001⟩. ⟨hal-01004423⟩