Palladium and copper-supported on charcoal : A heterogeneous multi-task catalyst for sequential Sonogashira-Click and Click-Heck reactions

Cybille Rossy (1, 2) , Jérôme Majimel (3) , Mona Tréguer-Delapierre (3) , Eric Fouquet (1) , François-Xavier Felpin (1)

1 ISM - Institut des Sciences Moléculaires
2 CEISAM - Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation
3 ICMCB - Institut de Chimie de la Matière Condensée de Bordeaux

This paper describes the development of one-pot sequential Sonogashira-Click and Click-Heck reactions by using Pd-Cu/C as a heterogeneous multi-task catalyst for the synthesis of heterocyclic structures. Details of the optimization studies and the substrate scope are discussed. These methodologies allow the preparation of functionalized triazoles in simple experimental conditions with inexpensive reagents.

Mots clés: Sonogashira; Click; Heck; Palladium; Copper; Heterogeneous bimetallic catalyst

Domaines: Matériaux

Cybille Rossy, Jérôme Majimel, Mona Tréguer-Delapierre, Eric Fouquet, François-Xavier Felpin. Palladium and copper-supported on charcoal : A heterogeneous multi-task catalyst for sequential Sonogashira-Click and Click-Heck reactions. Journal of Organometallic Chemistry, 2014, 755, pp.78-85. ⟨10.1016/j.jorganchem.2014.01.006⟩. ⟨hal-00974396⟩