2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties
Résumé
The 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide (EMPO), an easily prepared pyrroline-N-oxide has been tested as free radical scavenger. Spin adducts of superoxide, hydroxyl radical and other free radicals were characterized in phosphate buffer at pH 7.0 and 5.6. At pH 7 in phosphate buffer, the EMPO/O2-* spin adduct was estimated to be about 5 times more persistent than its DMPO analogue. Furthermore, its decay does not produce the EMPO/ HO* adduct.
Domaines
Autre
Origine : Fichiers produits par l'(les) auteur(s)
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