Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic Hepatitis B virus infection
Résumé
Chronic hepatitis B virus (HBV) infections remain a major problem public health problem worldwide, as well as a therapeutic challenge for clinicians. This review focuses on the main viral and host determinants involved in HBV persistence in infected cells. The mechanism of HBV resistance to nucleoside analogs are described as well as the concept for multiple drug therapy and combination with immunostimulatory approaches.
Fichier principal
ZoulimRevised.pdf (235.92 Ko)
Télécharger le fichier
ZoulimFiguresRvd.ppt (93 Ko)
Télécharger le fichier
Format : Autre