Phenotypes and Endotypes of Peach Allergy: What Is New?

Simona Barni , Davide Caimmi (1) , Fernanda Chiera , Pasquale Comberiati (2, 3) , Carla Mastrorilli (4) , Umberto Pelosi , Francesco Paravati , Gian Luigi Marseglia (5) , Stefania Arasi (6)

1 IDESP - Institut Desbrest de santé publique
2 University of Pisa - Università di Pisa
3 Sechenov First Moscow State Medical University
4 Polytechnic University of Bari / Politecnico di Bari
5 UNIPV - Università degli Studi di Pavia = University of Pavia
6 IRCCS Ospedale Pediatrico Bambino Gesù = Bambino Gesù Children’s Hospital

Peach allergy is emerging as a common type of fresh-fruit allergy in Europe, especially in the Mediterranean area. The clinical manifestations of peach allergy tend to have a peculiar geographical distribution and can range from mild oral symptoms to anaphylaxis, depending on the allergic sensitization profile. The peach allergen Pru p 7, also known as peamaclein, has recently been identified as a marker of peach allergy severity and as being responsible for peculiar clinical features in areas with high exposure to cypress pollen. This review addresses the latest findings on molecular allergens for the diagnosis of peach allergy, the clinical phenotypes and endotypes of peach allergy in adults and children, and management strategies, including immunotherapy, for peach allergy.

Domaines: Pédiatrie

Simona Barni, Davide Caimmi, Fernanda Chiera, Pasquale Comberiati, Carla Mastrorilli, et al.. Phenotypes and Endotypes of Peach Allergy: What Is New?. Nutrients, 2022, 14 (5), pp.998. ⟨10.3390/nu14050998⟩. ⟨hal-03704969⟩