Radiomics in PET imaging: a practical guide for newcomers

Fanny Orlhac (1) , Christophe Nioche (1) , Ivan Klyuzhin , Arman Rahmim , Irène Buvat (1)

1 LITO - Laboratoire d'Imagerie Translationnelle en Oncologie

Radiomics has undergone considerable development in recent years. In PET imaging, very promising results concerning the ability of handcrafted features to predict the biological characteristics of lesions and to assess patient prognosis or response to treatment have been reported in the literature. This article presents a checklist for designing a reliable radiomic study, gives an overview of the steps of the pipeline, and outlines approaches for data harmonization. Tips are provided for critical reading of the content of articles. The advantages and limitations of handcrafted radiomics compared to deep learning approaches for the characterization of PET images are also discussed.

Mots clés: Radiomics; PET; texture; heterogeneity; harmonization

Domaines: Imagerie; Médecine nucléaire

Fanny Orlhac, Christophe Nioche, Ivan Klyuzhin, Arman Rahmim, Irène Buvat. Radiomics in PET imaging: a practical guide for newcomers. PET Clinics, 2021, 16 (4), pp.597-612. ⟨hal-03320546⟩