Protease Inhibitors. Part 2. Weakly Basic Thrombin Inhibitors Incorporating Sulfonyl-Aminoguanidine Moieties as S1 Anchoring Groups: Synthesis and Structure-Activity Correlations

Brian Clare (1) , Andrea Scozzafava (2) , Fabrizio Briganti (2) , Bogdan Iorga (3) , Claudiu Supuran (2)

1 Murdoch University
2 LCBI-UniFI - Laboratorio di Chimica Bioinorganica [UniFI, Firenze] = Laboratory of Bioinorganic Chemistry [UniFI Florence]
3 University of Bucharest, Faculty of Chemistry, Department of Organic Chemistry, Biochemistry and Catalysis

Mots clés: Thrombin; Inhibition; Trypsin; Sulfonyl-aminoguanidines

Domaines: Chimie

Brian Clare, Andrea Scozzafava, Fabrizio Briganti, Bogdan Iorga, Claudiu Supuran. Protease Inhibitors. Part 2. Weakly Basic Thrombin Inhibitors Incorporating Sulfonyl-Aminoguanidine Moieties as S1 Anchoring Groups: Synthesis and Structure-Activity Correlations. Journal of Enzyme Inhibition and Medicinal Chemistry, 2000, 15 (3), pp.235-264. ⟨10.3109/14756360009040686⟩. ⟨hal-03161392⟩