Release studies of trans- anethole from β-cyclodextrin solid inclusion complexes by Multiple Headspace Extraction

Miriana Kfoury (1) , Lizette Auezova , Hélène Greige-Gerges , Kim Larsen , Sophie Fourmentin (1)

1 UCEIV - Unité de Chimie Environnementale et Interactions sur le Vivant

This study aimed to evaluate the effect of the preparation method, temperature and humidity on the release of aroma from β-cyclodextrin (β-CD) solid inclusion complexes (IC). Therefore β-CD/trans-anethole (β-CD/AN) IC were prepared by freeze-drying (FD) and co-precipitation coupled to FD (Cop-FD). Release experiments were performed at various temperatures and relative humidities (RH). Multiple headspace extraction-gas chromatography (MHE) was used to determine the loading capacity (LC) and encapsulation efficiency (EE%) and perform release studies. Results underlined that the quantification of encapsulated AN by MHE requires the IC dissolution. The release of AN was accelerated by increases in RH and temperature. However, it was quite negligible below 75% RH. The release behavior of AN was well simulated by Avrami's equation. Cop-FD IC retained more efficiently AN and the release depended on the preparation method and treatment conditions. Thus, the preparation method could be chosen based on the application.

Mots clés: β-Cyclodextrin; Controlled release; Inclusion complexes; Multiple headspace extraction; Relative humidity; Temperature

Domaines: Sciences du Vivant [q-bio]

Miriana Kfoury, Lizette Auezova, Hélène Greige-Gerges, Kim Larsen, Sophie Fourmentin. Release studies of trans- anethole from β-cyclodextrin solid inclusion complexes by Multiple Headspace Extraction. Carbohydrate Polymers, 2016, 151, pp.1245-1250. ⟨10.1016/j.carbpol.2016.06.079⟩. ⟨hal-02947870⟩