Effect of terbutaline (b2-agonist) on the level of post-effort arousal.

Christophe Gernigon (1, 2) , Giacomo Crivelli , Marie Amelie Le Fur (1) , Anaïs Lemieux (1) , Fabio Borrani , Guillaume Py (1) , Robin Candau (1)

1 UM - Université de Montpellier
2 EPSYLON - Dynamique des capacités humaines et des conduites de santé

Part of the ergogenic effects of ?2-agonists are believed to be due to their stimulating psychotropic effectsince? 2- adrenergic receptors avec ubiquitous. The purpose of the present study was to analyze thepsychological effects of Terbutaline, when this ?2-agonist was administered orally (8 mg) to athletes. Sevenhealthy males voluntarily participated in two sessions corresponding to two experimental conditions: ingestionof Terbutaline vs. ingestion of its placebo. Terbutaline or placebo was ingested 3 hr before performing anexercise on a cycloergometer until exhaustion at an intensity corresponding to 50% between the ventilatorythreshold and maximal oxygen uptake intensities.Right after the test,participants completed Russel,Weiss,andMendelsohn’s (1989) Affect Grid which measures affect along the dimensions of pleasure-displeasure andarousal-sleepiness. The ANOVAs showed a significant effect (p < .05) only for the arousal-sleepinessdimension.The ingestion of Terbutaline entailed a lower level of post-effort arousal than did the ingestion ofthe placebo. This unexpected tranquillizing effect may be interpreted as a negative secondary effect ofTerbutaline which was administered in supra-therapeutic doses in the present study. Future research isneeded to examine the psychological effects of Terbutaline at therapeutic doses.

Domaines: Psychologie et comportements

Christophe Gernigon, Giacomo Crivelli, Marie Amelie Le Fur, Anaïs Lemieux, Fabio Borrani, et al.. Effect of terbutaline (b2-agonist) on the level of post-effort arousal.. XIIIth European Congress on Sport Psychology of the European Federation of Sports Psychology (FEPSAC), Jul 2011, Madère, Portugal. ⟨hal-02933581⟩