Assessment of residential exposures to agricultural pesticides: A scoping review

Raphaëlle Teysseire (1, 2, 3) , Guyguy Manangama (1, 2) , Isabelle Baldi (1, 2) , Camille Carles (1, 2) , Patrick Brochard (1, 2) , Carole Bedos (4) , Fleur Delva (1, 2)

1 EPICENE - Cancer environnement
2 CHU Bordeaux
3 ARS NA - Agence Régionale de Santé Nouvelle-Aquitaine [Bordeaux]
4 ECOSYS - Ecologie fonctionnelle et écotoxicologie des agroécosystèmes

The assessment of residential exposure to agricultural pesticides is a major issue for public health, regulatory and management purposes. In recent years, research into this field has developed considerably. The purpose of this scoping review is to provide an overview of scientific literature characterizing residential exposure to agricultural pesticides and to identify potential gaps in this research area. This work was conducted according to the JBI and PRISMA guidelines. Three databases were consulted. At least two experts selected the eligible studies. Our scoping review enabled us to identify 151 articles published between 1988 and 2019 dealing with the assessment of residential exposure to agricultural pesticides. Of these, 98 (64.9%) were epidemiological studies investigating possible links between pesticide exposure and the onset of adverse health effects, principally cancers and reproductive outcomes. They predominantly used Geographic Information Systems and sometimes surveys or interviews to calculate surrogate exposure metrics, the most common being the amounts of pesticides applied or the surface area of crops around the dwelling. Twenty-six (17.2%) were observational measurement studies conducted to quantify levels of pesticide exposure and identify their possible determinants. These studies assessed exposure by measuring pesticides in biological and environmental matrices, mostly in urines and house dust. Finally, we found only eight publications (5.3%) that quantified the risk to human health due to residential exposure for management purposes, in which exposure was mainly determined using probabilistic models. Pesticide exposure appears to be largely correlated with the spatial organization of agriculture activities in a territory. The determinants and routes of exposure remain to be explored to improve the conduct of epidemiological and risk assessment studies and to help prevent future exposures. Improvement could be expected from small-scale studies combining different methods of exposure assessment.

Domaines: Sciences de l'environnement; Santé; Santé publique et épidémiologie; Sciences agricoles

Raphaëlle Teysseire, Guyguy Manangama, Isabelle Baldi, Camille Carles, Patrick Brochard, et al.. Assessment of residential exposures to agricultural pesticides: A scoping review. PLoS ONE, 2020, 15 (4), ⟨10.1371/journal.pone.0232258⟩. ⟨hal-02779890⟩