Epidemiology, molecular virology and diagnostics of Schmallenberg virus, an emerging orthobunyavirus in Europe

Virginie Doceul (1) , Estelle Lara (1) , Corinne Sailleau (1) , Guillaume Belbis (2) , Jennifer Richardson (1) , Emmanuel Breard (1) , Cyril Viarouge (1) , Morgane Dominguez (3) , Pascal Hendrikx (3) , Didier Calavas (3) , Alexandra Desprat (1) , Jérôme Languille (4) , Loic Comtet (5) , Philippe Pourquier (5) , Jean Francois J. F. Eleouet (6) , Bernard B. Delmas (6) , Philippe Marianneau (3) , Damien Vitour (1) , Stéphan Zientara (1)

1 VIRO - Virologie UMR1161
2 Université Paris-Est (COMUE)
3 ANSES - Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail
4 Ministère de l'agriculture
5 IDvet [Grabels]
6 VIM (UR 0892) - Unité de recherche Virologie et Immunologie Moléculaires

After the unexpected emergence of Bluetongue virus serotype 8 (BTV-8) in northern Europe in 2006, another arbovirus, Schmallenberg virus (SBV), emerged in Europe in 2011 causing a new economically important disease in ruminants. The virus, belonging to the Orthobunyavirus genus in the Bunyaviridae family, was first detected in Germany, in The Netherlands and in Belgium in 2011 and soon after in the United Kingdom, France, Italy, Luxembourg, Spain, Denmark and Switzerland. This review describes the current knowledge on the emergence, epidemiology, clinical signs, molecular virology and diagnosis of SBV infection.

Mots clés: CALIFORNIA SEROGROUP BUNYAVIRUSES; VIRAL INTERFERON ANTAGONIST; TIME RT-PCR; AKABANE VIRUS; BUNYAMWERA-VIRUS; CONGENITAL-ABNORMALITIES; FEVER VIRUS

Mots clés: LA-CROSSE VIRUS; NONSTRUCTURAL PROTEIN NSS; BLUETONGUE VIRUS

Domaines: Sciences du Vivant [q-bio]

Virginie Doceul, Estelle Lara, Corinne Sailleau, Guillaume Belbis, Jennifer Richardson, et al.. Epidemiology, molecular virology and diagnostics of Schmallenberg virus, an emerging orthobunyavirus in Europe. Veterinary Research, 2013, 44 (31), ⟨10.1186/1297-9716-44-31⟩. ⟨hal-02651632⟩