Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance

Clément Offret (1) , Florie Desriac (2, 3, 4) , Patrick Le Chevalier (1) , Jérôme Mounier (1) , Camille Jégou (5) , Yannick Fleury (1)

1 UBO - Université de Brest
2 INRA - Institut National de la Recherche Agronomique
3 UA - Université d'Artois
4 ULCO - Université du Littoral Côte d'Opale
5 LUBEM - Laboratoire Universitaire de Biodiversité et Ecologie Microbienne

This review is dedicated to the antimicrobial metabolite-producing Pseudoalteromonas strains. The genus Pseudoalteromonas hosts 41 species, among which 16 are antimicrobial metabolite producers. To date, a total of 69 antimicrobial compounds belonging to 18 different families have been documented. They are classified into alkaloids, polyketides, and peptides. Finally as Pseudoalteromonas strains are frequently associated with macroorganisms, we can discuss the ecological significance of antimicrobial Pseudoalteromonas as part of the resident microbiota.

Mots clés: Pseudoalteromonas; antimicrobial metabolites; alkaloid; polyketide; genome mining; marine host-associated microbiota; probiotic

Mots clés: non ribosomal peptide

Domaines: Sciences du Vivant [q-bio]

Clément Offret, Florie Desriac, Patrick Le Chevalier, Jérôme Mounier, Camille Jégou, et al.. Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance. Marine drugs, 2016, 14 (7), pp.1-26. ⟨10.3390/md14070129⟩. ⟨hal-02638821⟩