Deficit of fat free mass in very preterm infants at discharge is associated with neurological impairment at age 2 years

Anne Frondas Chauty (1, 2, 3) , Laure Simon (1, 2, 3) , Cyril Flamant (1, 2, 3, 4) , Matthieu Hanf (4, 5) , Dominique D. Darmaun (1, 2) , Jean-Christophe Rozé (1, 2, 3, 4)

1 PhAN - Physiopathologie des Adaptations Nutritionnelles
2 Centre de Recherche en Nutrition Humaine
3 Department of Neonatal Medicine
4 CHU Nantes - Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
5 UVSQ - Université de Versailles Saint-Quentin-en-Yvelines

Preterm infants have a deficit of fat-free mass accretion during hospitalization. This study suggests that z score of fat-free mass at discharge is associated with neurologic outcome (P = .003) at 2 years of age, independent of sex, gestational age, and birth weight z score. Interventions to promote quality of growth should be considered.

Domaines: Pédiatrie

Anne Frondas Chauty, Laure Simon, Cyril Flamant, Matthieu Hanf, Dominique D. Darmaun, et al.. Deficit of fat free mass in very preterm infants at discharge is associated with neurological impairment at age 2 years. The Journal of Pediatrics, 2018, 196, pp.301-304. ⟨10.1016/j.jpeds.2017.12.017⟩. ⟨hal-02621086⟩