The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

Mena Abdel-Nour , Leticia Carneiro , Jeffrey Downey (1) , Jessica Tsalikis , Ahmed Outlioua , Dave Prescott , Leandro Silva da Costa , Elise Hovingh , Armin Farahvash , Ryan Gaudet , Raphael Molinaro , Rob van Dalen , Charles Lau , Farshad Azimi , Nichole Escalante , Aaron Trotman-Grant , Jeffrey Lee , Scott Gray-Owen , Maziar Divangahi (1) , Jane-Jane Chen , Dana Philpott , Damien Arnoult (2) , Stephen E. Girardin

1 MUHC - McGill University Health Center [Montreal]
2 INSERM U1197

Domaines: Biologie cellulaire

Mena Abdel-Nour, Leticia Carneiro, Jeffrey Downey, Jessica Tsalikis, Ahmed Outlioua, et al.. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science, 2019, 365 (6448), pp.eaaw4144. ⟨10.1126/science.aaw4144⟩. ⟨hal-02372326⟩