Aircraft noise exposure and saliva cortisol in a pooled-analysis from seven European countries

Clémence Baudin (1) , Marie Lefevre (1) , Jenny Selander (2) , Patricia Champelovier (3) , Jacques Lambert (3) , Bernard Laumon (4) , Anne-Sophie Evrard (1)

1 UMRESTTE UMR T9405 - Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement
2 Institute of Environmental Medicine
3 IFSTTAR/AME/LTE - Laboratoire Transports et Environnement
4 IFSTTAR/TS2 - Département Transport, Santé, Sécurité

Introduction : HYENA (HYpertension and Exposure to Noise near Airports), a well-known study on the health effects of aircraft noise, involved 4,861 participants from six European countries (except France). DEBATS (Discussion on the health effects of aircraft noise), a study with a similar protocol, included 1,244 participants from France. Saliva samples were obtained for 439 and 954 participants in HYENA and DEBATS respectively, to determine cortisol concentration as a possible marker of noise-induced stress. Associations were found between aircraft noise and cortisol levels in each study separately, but they were not consistent between the two studies. The objective of the present study was to combine datasets to improve statistical power. Methods : We investigated the associations between aircraft noise levels and, the log-cortisol levels in the morning and in the evening, and the log-relative variation per hour, adjusted for relevant confounders. Results : We found evidence in women for an increase in the log-evening cortisol level ?=0.09 (95%CI 0.01;0.17), and for flattening of the log-relative variation per hour ?=-0.09 (95%CI -0.16;-0.02), with a LDEN 10-dB(A) increase, but no significant effects in men. Conclusions : These findings provide some support for psychological stress induced by aircraft noise exposure, resulting in disruption of hormonal rhythms.

Mots clés: AIRCRAFT NOISE EXPOSURE; CORTISOL LEVELS; EUROPE

Domaines: Santé publique et épidémiologie

Clémence Baudin, Marie Lefevre, Jenny Selander, Patricia Champelovier, Jacques Lambert, et al.. Aircraft noise exposure and saliva cortisol in a pooled-analysis from seven European countries. 59th ERSA, Aug 2019, LYON, France. 25 p. ⟨hal-02349740⟩