Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice

Alistair T. Pagnamenta (1) , Pierre Heemeryck (2) , Hilary Martin (3) , Christophe Bosc (2) , Leticia Peris (4, 2) , Ivy Uszynski (5) , Sylvie Gory-Fauré (2) , Simon Couly (6) , Charu Deshpande (7) , Ata Siddiqui (8) , Alaa Elmonairy (9) , Sandeep Jayawant (10) , Sarada Murthy (11) , Ian Walker (12) , Lucy Loong (13) , Peter Bauer (14) , Frédérique Vossier (2) , Eric Denarier (4, 2) , Tangui Tm Maurice (6) , Emmanuel L. Barbier (2) , Jean-Christophe Deloulme (2) , Jenny Taylor (15) , Edward Blair (16) , Annie Andrieux (4, 2) , Marie-Jo Moutin (2)

1 Oxford NIHR Biomedical Research Centre
2 GIN - [GIN] Grenoble Institut des Neurosciences
3 The Wellcome Trust Sanger Institute [Cambridge]
4 GPC - Groupe Physiopathologie du Cytosquelette
5 GIN - [GIN] Grenoble Institut des Neurosciences
6 MMDN - Mécanismes moléculaires dans les démences neurodégénératives
7 Guy's Hospital [London]
8 Kings College Hospital
9 Ministry of Health [Koweït]
10 John Radcliffe Hospital [Oxford University Hospital]
11 Upton Hospital [Slough, Royaume-uni]
12 Wexham Park Hospital [Slough, Royaume-Uni]
13 Oxford University Hospitals NHS Trust
14 CENTOGENE AG
15 University of Oxford
16 Department of Clinical Genetics, Oxford Regional Genetics Service

Domaines: Morphogenèse

Alistair T. Pagnamenta, Pierre Heemeryck, Hilary Martin, Christophe Bosc, Leticia Peris, et al.. Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice. Human Molecular Genetics, 2019, ⟨10.1093/hmg/ddz186⟩. ⟨hal-02345641⟩