Nuclear magnetic resonance monitoring of centrifugal partition chromatography in pH-zone-refining mode

Manfred Spraul , Ulrich Braumann , Jean-Hugues Renault (1) , Philippe Thépenier (1) , Jean-Marc Nuzillard (1)

1 Laboratoire de Pharmacognosie

The coupling of centrifugal partition chromatography to NMR spectroscopy as detection and analysis method is investigated. Separation of a test mixture of three N-2,4-dinitrophenyl amino acids was performed in pH-zone-refining elution mode. The NMR and chromatography instrumentation was very similar to the one of the LC–NMR technique.

Domaines: Chimie analytique; Chimie organique

Manfred Spraul, Ulrich Braumann, Jean-Hugues Renault, Philippe Thépenier, Jean-Marc Nuzillard. Nuclear magnetic resonance monitoring of centrifugal partition chromatography in pH-zone-refining mode. Journal of Chromatography A, 1997, 766 (1-2), pp.255-260. ⟨10.1016/S0021-9673(96)01038-2⟩. ⟨hal-01968171⟩