SimCells, an advanced software for multicellular modeling Application to tumoral and blood vessel co-development

Pascal Ballet (1)

1 LaTIM - Laboratoire de Traitement de l'Information Medicale

New biomedical advances at cellular level give the possibility to develop more and more accurate computational models of cells. Moreover, the increasing power of graphical processor units allows the simulation of millions of interacting virtual cells. This paper summarizes efforts made to create multicellular simulators, their attended benefits and their inevitable drawbacks. In particular, it presents the new software SimCells that simulate the dynamics of multicellular systems using a graphically programmable multiagent system. A fully functional example of the tumoral and blood vessel co-development is also detailed.

Domaines: Système multi-agents [cs.MA]; Modélisation et simulation; Bio-informatique [q-bio.QM]

Pascal Ballet. SimCells, an advanced software for multicellular modeling Application to tumoral and blood vessel co-development. 2018. ⟨hal-01853293⟩