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Intramolecular cyclization of N-phenyl N′(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40

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https://hal.archives-ouvertes.fr/hal-01677555
Contributor : Emmanuel Moreau <>
Submitted on : Monday, January 8, 2018 - 2:37:05 PM
Last modification on : Tuesday, March 17, 2020 - 2:32:09 AM

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Emmanuel Moreau, Anna Trzeciakiewicz, Sébastien Fortin, René C.-Gaudreault, Jacques Lacroix, et al.. Intramolecular cyclization of N-phenyl N′(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40. Biochemical Pharmacology, Elsevier, 2011, 81 (9), pp.1116 - 1123. ⟨10.1016/j.bcp.2011.02.014⟩. ⟨hal-01677555⟩

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