Incidence of skin cancers during 5-year follow-up after stopping antioxidant vitamins and mineral supplementation

Khaled Ezzedine (1) , Julie Latreille (2) , Emmanuelle Kesse-Guyot (3) , Pilar Galan (3) , Serge Hercberg (4) , Christiane Guinot (5, 6) , Denis Malvy (7)

1 Service de Dermatologie et Dermatologie Pédiatrique
2 CNAM Paris - Centre d'enseignement Cnam Paris
3 UREN - Unité de Recherche en Epidémiologie Nutritionnelle
4 CRNH-IDF - Centre de Recherche en Nutrition Humaine d'Ile-de-France
5 CERIES - CENTRE DE RECHERCHES ET D'INVESTIGATIONS EPIDERMIQUES ET SENSORIELLES
6 UT - Université de Tours
7 Service de médecine interne et maladies tropicales

In the SU.VI.MAX study, antioxidant supplementation for 7.5 years was found to increase skin cancer risk in women but not in men.

Total skin cancer incidence, including melanoma, squamous cell carcinoma and basal cell carcinoma.

Mots clés: Antioxidants; Dietary supplements; Skin cancer; Randomised controlled trial; Post-intervention follow-up; BETA-CAROTENE; OXIDATIVE STRESS; SECONDARY PREVENTION; TRIAL; RISK; MORTALITY; CARCINOGENESIS

Mots clés: Nutrition; CUTANEOUS MELANOMA; MEN; EPIDEMIOLOGY

Domaines: Sciences du Vivant [q-bio]

Khaled Ezzedine, Julie Latreille, Emmanuelle Kesse-Guyot, Pilar Galan, Serge Hercberg, et al.. Incidence of skin cancers during 5-year follow-up after stopping antioxidant vitamins and mineral supplementation. European Journal of Cancer, 2010, 46 (18), pp.3316 - 3322. ⟨10.1016/j.ejca.2010.06.008⟩. ⟨hal-01614393⟩