Emergence of Copper-mediated formation of C-C bonds

Carine Maaliki (1) , Emilie Thiery (2, 1) , Jérôme Thibonnet (2, 1)

1 UT - Université de Tours
2 UMR ISP - Infectiologie et Santé Publique

Copper-catalyzed cross-coupling reactions have found widespread application in carbon-carbon or carbon-heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper-mediated formation of carbon-carbon bonds illustrated by different coupling reactions: cross-dehydrogenative coupling, decarboxylative cross-coupling, Sonogashira-type reactions, Suzuki-type reactions, and Neigishi-type reactions. Domino reactions and, finally, more atypical reactions are also illustrated.

Mots clés: synthetic methods; C-C coupling; dehydrogenative coupling; decarboxylative coupling; domini reactions; Copper; carbon carbon bond

Mots clés: décarboxylation; liaison carbone carbone; déhydrogenase

Domaines: Chimie organique

Carine Maaliki, Emilie Thiery, Jérôme Thibonnet. Emergence of Copper-mediated formation of C-C bonds. European Journal of Organic Chemistry, 2017, 2017 (2), pp.209-228. ⟨10.1002/ejoc.201600540⟩. ⟨hal-01601331⟩