The evolution of bicontinuous polymeric nanospheres in aqueous solution

B. E. Mckenzie (1, 2) , J. F. de Visser (1, 2) , G. Portale (3) , D. Hermida-Merino (3) , H. Friedrich (1, 2) , P. H. H. Bomans (4, 1, 2) , W. Bras (3) , O. R. Monaghan (5) , S. J. Holder (5) , N. A. J. M. Sommerdijk (4, 1, 2)

1 Eindhoven Univ Technol, Lab Mat & Interface Chem, POB 513, NL-5600 MB Eindhoven, Netherlands
2 Eindhoven Univ Technol, Soft Matter Cryo TEM Res Unit, POB 513, NL-5600 MB Eindhoven, Netherlands
3 ESRF - European Synchrotron Radiation Facility
4 Eindhoven Univ Technol, Inst Complex Mol Syst, POB 513, NL-5600 MB Eindhoven, Netherlands
5 Univ Kent, Sch Phys Sci, Funct Mat Grp, Canterbury CT2 7NH, Kent, England

Complex polymeric nanospheres in aqueous solution are desirable for their promising potential in encapsulation and templating applications. Understanding how they evolve in solution enables better control of the final structures. By unifying insights from cryoTEM and small angle X-ray scattering (SAXS), we present a mechanism for the development of bicontinuous polymeric nanospheres (BPNs) in aqueous solution from a semi-crystalline comb-like block copolymer that possesses temperature-responsive functionality. During the initial stages of water addition to THF solutions of the copolymer the aggregates are predominantly vesicles; but above a water content of 53% irregular aggregates of phase separated material appear, often microns in diameter and of indeterminate shape. We also observe a cononsolvency regime for the copolymer in THF-water mixtures from 22 to 36%. The structured large aggregates gradually decrease in size throughout dialysis, and the BPNs only appear upon cooling the fully aqueous dispersions from 35 degrees C to 5 degrees C. Thus, the final BPNs are ultimately the result of a reversible temperature-induced morphological transition

Domaines: Chimie

B. E. Mckenzie, J. F. de Visser, G. Portale, D. Hermida-Merino, H. Friedrich, et al.. The evolution of bicontinuous polymeric nanospheres in aqueous solution. Soft Matter, 2016, 12 (18), pp.4113-4122. ⟨10.1039/c6sm00053c⟩. ⟨hal-01572710⟩