In vivo digestion of infant formula in piglets: protein digestion kinetics and their potential bioactivity

Karima Bouzerzour (1) , Isabelle Luron (2, 2) , F. Morgan (3) , I. Cuinet (3) , Julien Jardin (1) , Didier Dupont (1)

1 STLO - Science et Technologie du Lait et de l'Oeuf
2 SENAH - Systèmes d'élevage, nutrition animale et humaine
3 LACTALIS NUTRITION - LACTALIS

Infant formula (IF) are major sources of proteins for the neonate and represent the only alternative when breast-feeding is not possible. During IF manufacture, protein structures are modified by processing conditions. The resistance of IF proteins to digestion in different compartment of the digestive tract is still unknown. Aim. The objective was to study the digestion of IF milk proteins i.e. caseins (Cns), b-lactoglobulin (b-lg) and a-lactalbumin (a-la), over time in the stomach, jejunum and ileum of 18 piglets (taken as a model of human neonates), and to identify peptides present in the small intestine.

Mots clés: formulation; protéine bioactive; cinétique; animal models; intestine; children; milk; human health

Mots clés: digestion; modèle animal; cinétique d'absorption; intestin; enfant; formulation alimentaire; lait; peptide bioactif; santé humaine

Domaines: Ingénierie des aliments; Alimentation et Nutrition

Karima Bouzerzour, Isabelle Luron, F. Morgan, I. Cuinet, Julien Jardin, et al.. In vivo digestion of infant formula in piglets: protein digestion kinetics and their potential bioactivity. The International Symposium: Dietary Protein for Human Health, Mar 2011, Auckland, New Zealand. ⟨hal-01454383⟩