Genome sequences of two Staphylococcus aureus ovine strains that induce severe (strain O11) and mild (strain O46) mastitis

Caroline Le Maréchal (1, 2) , David Hernandez (3) , Jacques Schrenzel (3) , Sergine Even (1) , Nadia Berkova (1) , Richard Thiéry (4) , Eric Vautor (4) , J. Ross Fitzgerald (5) , Patrice François (3) , Yves Le Loir (1)

1 STLO - Science et Technologie du Lait et de l'Oeuf
2 Laboratoire de Sophia-Antipolis, Unité Pathologie des Ruminants
3 Service of Infectious Diseases - Genomic Research Laboratory
4 Laboratoire de Sophia-Antipolis, Unité Pathologie des Ruminants
5 Royal (Dick) School of Veterinary Studies - The Roslin Institute and Centre for Infectious Diseases

Staphylococcus aureus is a major etiological agent of mastitis in ruminants. We report here the genome sequences of two ovine strains that were isolated from gangrenous (strain O11) and subclinical (strain O46) ewe mastitis. Both strains belong to the same clonal complex. Despite this close genotypic relationship, the two isolates were shown to reproducibly induce highly divergent types of infections, either severe (O11) or mild (O46) mastitis, in an experimental ewe model.

Mots clés: SEQUENCE; nucleic sequence; numerical models

Mots clés: génome; séquence nucleique; modèle

Domaines: Microbiologie et Parasitologie

Caroline Le Maréchal, David Hernandez, Jacques Schrenzel, Sergine Even, Nadia Berkova, et al.. Genome sequences of two Staphylococcus aureus ovine strains that induce severe (strain O11) and mild (strain O46) mastitis. Journal of Bacteriology, 2011, 193 (9), pp.2353-2354. ⟨10.1128/JB.00045-11⟩. ⟨hal-01454188⟩