Phosphatidylserine in atherosclerosis

Maryam Darabi (1) , Anatol Kontush (1)

1 ICAN - Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases

Purpose of review: It is now widely acknowledged that phosphatidylserine is a multifunctional bioactive lipid. In this review, we focus on the function of phosphatidylserine in modulating cholesterol metabolism, influencing inflammatory response and regulating coagulation system, and discuss promising phosphatidylserine-based therapeutic approaches and detection techniques in atherosclerosis.

Domaines: Médecine humaine et pathologie

Maryam Darabi, Anatol Kontush. Phosphatidylserine in atherosclerosis. Current Opinion in Lipidology, 2016, 27 (4), pp.414 - 420. ⟨10.1097/MOL.0000000000000298⟩. ⟨hal-01382705⟩