Interaction between olfaction and food intake: metabolic state drives changes in the astroglial deployment within the olfactory bulb glomeruli in rats

Virginie Daumas-Meyer (1) , Gaelle Champeil Potokar (1) , Catherine Papillon (1) , Patrice Dahirel (1) , Marielle Levillain (1) , Patrice Congar (1) , Isabelle Denis (1)

1 NBO - Neurobiologie de l'olfaction

Olfaction participates in the elaboration of the hedonic value of foods, food choice and the regulation of food intake. Reciprocally, the detection of food odors is influenced by metabolic state and thereby contributes to the initiation and termination of eating behavior. Fasting increases olfactory performances, notably by increasing neuronal activation in the olfactory bulb (OB) (Prud’homme et al, 2009), the first integration site of olfactory signals towards the central nervous system. Within the OB glomeruli, glutamatergic synapses between olfactory sensory neurons and mitral cells are regulated by periglomerular neurons and astrocytes.

Domaines: Neurosciences [q-bio.NC]; Alimentation et Nutrition

Virginie Daumas-Meyer, Gaelle Champeil Potokar, Catherine Papillon, Patrice Dahirel, Marielle Levillain, et al.. Interaction between olfaction and food intake: metabolic state drives changes in the astroglial deployment within the olfactory bulb glomeruli in rats. 2. Journées thématiques de la Société des Neurosciences, May 2016, Tours, France. 2016. ⟨hal-01345504⟩