Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: mid-season analysis 2012/13

J. Mcmenamin , N. Andrews , C. Robertson (1, 2) , D. Fleming , H. Durnall , B. Von Wissmann , J. Ellis , A. Lackenby , S. Cottrell , B. Smyth , M. Zambon , C. Moore , J. Watson , R. Pebody

1 University of Strathclyde [Glasgow]
2 IPRI - International Prevention Research Institute

The early experience of the United Kingdom (UK) is that influenza B has dominated the influenza 2012/13 season. Overall trivalent influenza vaccine (TIV) adjusted vaccine effectiveness (VE) against all laboratory-confirmed influenza in primary care was 51% (95% confidence interval (CI): 27% to 68%); TIV adjusted VE against influenza A alone or influenza B alone was 49% (95% CI: -2% to 75%) and 52% (95% CI: 23% to 70%) respectively. Vaccination remains the best protection against influenza.

Mots clés: Adolescent Adult Age Distribution Aged Aged; 80 and over Case-Control Studies Child Child; Preschool Female Great Britain/epidemiology Humans Infant Infant; Newborn Influenza A virus/genetics/immunology/*isolation & purification Influenza B virus/genetics/immunology/*isolation & purification Influenza Vaccines/*administration & dosage/immunology Influenza; Human/diagnosis/epidemiology/*prevention & control/virology Logistic Models Male Middle Aged Odds Ratio Primary Health Care Questionnaires Real-Time Polymerase Chain Reaction *Seasons Sentinel Surveillance Treatment Outcome Vaccination/statistics & numerical data Young Adult

Domaines: Santé publique et épidémiologie

J. Mcmenamin, N. Andrews, C. Robertson, D. Fleming, H. Durnall, et al.. Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: mid-season analysis 2012/13. Euro Surveill, 2013, 18 (5). ⟨hal-01261733⟩