CIDANE: Comprehensive Isoform Discovery and Abundance Estimation

Stefan Canzar (1) , Andreotti Sandro (2) , David Weese (2) , Reinert Knut (2) , Klau Gunnar (3, 4)

1 Johns Hopkins University School of Medicine [Baltimore]
2 Department of Mathematics and Computer Science
3 ERABLE - Equipe de recherche européenne en algorithmique et biologie formelle et expérimentale
4 CWI - Centrum voor Wiskunde en Informatica

High-throughput sequencing of cellular RNA (RNA-seq) allows to assess the set of all RNA molecules, the transcriptome, produced by a cell at a high resolution, under various conditions. The assembly of short sequencing reads to full-length transcripts, however, poses profound challenges to bioinformatics tools.

Domaines: Bio-informatique [q-bio.QM]

Stefan Canzar, Andreotti Sandro, David Weese, Reinert Knut, Klau Gunnar. CIDANE: Comprehensive Isoform Discovery and Abundance Estimation. Research in Computational Molecular Biology (RECOMB), Apr 2015, Warsaw, Poland. pp.60-84, ⟨10.1007/978-3-319-16706-0_8⟩. ⟨hal-01248849⟩