Preprocessing and analysis of microarray images from integrated lensless bio-photonic sensors

Abstract : A new integrated lensless bio-photonic sensors is being developed. It replaces the ordinary slide supporting the DNA spots, and the complex, large and expensive hybridisation and the scanner reading system, by a sandwich of well defined chemical and optical layers grafted onto a CCD sensor. The upper layer of the new biochip performs the biological function. Due to the architecture of the biochip leading to a lensless imaging of the spots directly on the sensor pixels, the images produced will have novel characteristics beyond the analysis capacity of reading software packages of microarray analysis. In this framework, specific image processing and statistical data analysis algorithms have been developed in order to assess and to quantify these images
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Communication dans un congrès
SPIE Photonics Europe 2008: Optical and Digital Image Processing, Apr 2008, Strasbourg, France. SPIE, 7000, 12p, 2008, <10.1117/12.781377>
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https://hal-mines-paristech.archives-ouvertes.fr/hal-00569449
Contributeur : Isabelle Olzenski <>
Soumis le : vendredi 25 février 2011 - 10:33:22
Dernière modification le : mardi 12 septembre 2017 - 11:40:39

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Jesus Angulo, Christian Lajaunie, Michel Bilodeau, Lucio Martinelli, Françoise Le Boulaire, et al.. Preprocessing and analysis of microarray images from integrated lensless bio-photonic sensors. SPIE Photonics Europe 2008: Optical and Digital Image Processing, Apr 2008, Strasbourg, France. SPIE, 7000, 12p, 2008, <10.1117/12.781377>. <hal-00569449>

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