Soluble programmed death‐1 (sPD‐1) as predictor of early surgical outcomes of paediatric cystic echinococcosis

Eya Ben Salah (1) , Wahiba Sakly (1) , Coralie Barrera (2) , Sana Mosbahi (3) , Anne-Pauline Bellanger (2) , Rabeb Farhani (3) , Amine Ksia (3) , Bruno Gottstein (4) , Abdellatif Nouri (3) , Hamouda Babba (1) , Laurence Millon (5)

1 LP3M-LR12ES08 - Laboratoire de Parasitologie-Mycologie Médicale et Moléculaire [Monastir, Tunisie]
2 LCE - Laboratoire Chrono-environnement (UMR 6249)
3 Department of Paediatric Surgery and LR12SP13
4 Institute for Infectious Diseases, Faculty of Medicine, University of Berne, 3001 Berne, Switzerland
5 Service de parasitologie et mycologie [CHRU de Besançon]

Following treatment, cystic echinococcosis (CE) exhibits a relatively high relapse rate. Here, we evaluated the value of soluble programmed death-1 (sPD-1), sPD-1 ligand (sPD-L1) and anti-recP29 antibody concentrations, as predictors of early surgical treatment outcomes in young CE-affected patients.

Mots clés: children; cystic echinococcosis; follow-up; post-surgical outcome; recP29; sPD-1; sPD-L1

Domaines: Santé

Eya Ben Salah, Wahiba Sakly, Coralie Barrera, Sana Mosbahi, Anne-Pauline Bellanger, et al.. Soluble programmed death‐1 (sPD‐1) as predictor of early surgical outcomes of paediatric cystic echinococcosis. Parasite Immunology, 2021, 43 (3), pp.e12809. ⟨10.1111/pim.12809⟩. ⟨hal-03316048⟩