Genotypic study of Citrobacter koseri , an emergent platelet contaminant since 2012 in France

Audrey Emery (1) , Nadine Marpaux (2) , Christian Naegelen (2) , Benoit Valot (3) , Pascal Morel , Didier Hocquet (3, 1)

1 CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon
2 EFS BFC - Etablissement français du sang [Bourgogne-Franche-Comté]
3 LCE - Laboratoire Chrono-environnement (UMR 6249)

Transfusion-transmitted bacterial infection is a rare occurrence but the most feared complication in transfusion practices. Between 2012 and 2017, five cases of platelet concentrates (PCs) contaminated with the bacterial pathogen Citrobacter koseri (PC-Ck) have been reported in France, with two leading to the death of the recipients. We tested the possibilities of the emergence of a PC-specific clone of C. koseri (Ck) and of specific bacterial genes associated with PC contamination.

Domaines: Médecine humaine et pathologie; Microbiologie et Parasitologie

Audrey Emery, Nadine Marpaux, Christian Naegelen, Benoit Valot, Pascal Morel, et al.. Genotypic study of Citrobacter koseri , an emergent platelet contaminant since 2012 in France. Transfusion, 2020, 60 (2), pp.245-249. ⟨10.1111/trf.15617⟩. ⟨hal-02541556⟩