Fatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient.

Guillaume Miltgen , Jonathan Paillot (1) , Claire Vanlemmens (2) , Vincent Di Martino , Bruno Heyd , Laurence Millon (3) , Anne-Pauline Bellanger (3)

1 CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon
2 Service d'hépatologie
3 LCE - Laboratoire Chrono-environnement (UMR 6249)

The risk of Toxoplasma gondii infection in solid organ transplant recipients is well known but mainly after heart transplantation. We discuss a case of acute respiratory distress caused by Toxoplasma gondii on Day 32 after liver transplantation. The reported case, which is extremely rare, emphasizes how direct examination and Quantitative Polymerase Chain Reaction (QPCR) in broncholaveolar lavage help to diagnose the infection. Given Trimethoprim/Sulfamethoxazole toxicity, systematic prescription of Toxoplasma gondii chemoprophylaxis is not commonly approved in liver transplantation.

Domaines: Santé

Guillaume Miltgen, Jonathan Paillot, Claire Vanlemmens, Vincent Di Martino, Bruno Heyd, et al.. Fatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient.. Microbiologica -Bologna-, 2016, 39 (2), pp.160-2. ⟨hal-01368318⟩