Confirmation of quantitative trait loci affecting fatness in chickens

Danyel G.J. Jennen , Addie L.J. Vereijken , Henk Bovenhuis , Richard M.P.A. Crooijmans , Jan J. van Der Poel , Martien A.M. Groenen

In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G$_{2})$ onwards until generation 9 (G$_{9}$) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G$_{9}$ population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold.

Mots clés: quantitative trait loci; advanced intercross line; chicken; fatness traits

Domaines: Génétique animale

Danyel G.J. Jennen, Addie L.J. Vereijken, Henk Bovenhuis, Richard M.P.A. Crooijmans, Jan J. van Der Poel, et al.. Confirmation of quantitative trait loci affecting fatness in chickens. Genetics Selection Evolution, 2005, 37 (2), pp.215-228. ⟨hal-00894485⟩