Automatic evaluation of the peri-infarct area of myocardial infarction from delayed enhancement MRI

Alain Lalande (1) , Vanya V. Valindria (1) , Marion Angue (1) , Nicolas Vignon (1) , Alexandre Cochet (1) , François Brunotte (1)

1 Le2i - Laboratoire Electronique, Informatique et Image [UMR6306]

Delay Enhancement - Magnetic Resonance Imaging (DE-MRI) can be considered as the gold standard for the assessment of myocardial viability after myocardial infarction (MI). Around the infarcted areas that appear with hyper-enhanced signal, there is a peri-infarct border zone that may be an important arrhythmogenic substrate. The extent of this area is an independent predictor of post-MI mortality (1). However, it is difficult to separate peri-infarct border zones from infarct core or normal areas, because of their intermediate signal intensity. We propose a new automatic approach to detect this area, based on a modified Gaussian Mixture Model (GMM) and spatial-weighted fuzzy clustering.

Domaines: Imagerie médicale

Alain Lalande, Vanya V. Valindria, Marion Angue, Nicolas Vignon, Alexandre Cochet, et al.. Automatic evaluation of the peri-infarct area of myocardial infarction from delayed enhancement MRI. European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Oct 2012, Lisbonne, Portugal. pp.123. ⟨hal-00787301⟩