Palladium-Catalyzed Cross-couplings of Lithium Arylzincates with Aromatic Halides. Synthesis of Analogues of Isomeridianin G and Evaluation as GSK- 3 Inhibitors
Résumé
Several analogues of Isomeridianin G have been synthesized using as a key step palladium-catalyzed crosscoupling reactions of lithium triorganozincates. The latter have been prepared by deprotonative lithiation followed by transmetalation using ZnCl2*TMEDA (1/3 equiv).
Domaines
Chimie organique
Fichier principal
Palladium-Catalyzed_Cross-couplings_of_Lithium_Arylzincates_with_Aromatic.pdf (953.6 Ko)
Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...