Physiological responses to chronic heat exposure in an aging non-human primate species, the gray mouse lemur ()

J. Terrien , S. Blanc (1) , P. Zizzari (2) , J. Epelbaum (2) , F. Aujard

1 UNISTRA - Université de Strasbourg
2 U894 - Centre de Psychiatrie et Neurosciences

Epidemiological evidence related to increased death from hyperthermia suggests higher frailty in the elderly when exposed to high ambient temperatures. Despite the recent awareness of such public health problems, integrative studies investigating the effects of age on the physiological responses to heat wave thermal conditions remain scarce. Daily rhythmicity of core temperature (T) and locomotor activity (LA), as well as parameters representative of energy balance and IGF-1 levels which are involved in the aging process and stress resistance, were monitored in a non-human primate species, the gray mouse lemur (). Adult and aged animals, acclimated to long days (LD) or short days (SD), were monitored during 8-day periods of exposure to 25°C and 34°C.

Mots clés: BM; BMG; CI; DEE; IGF-1; LA; LD; LME; PP; heat exposure; core temperature; non-human primate; energy balance; water turnover

Domaines: Gériatrie et gérontologie

J. Terrien, S. Blanc, P. Zizzari, J. Epelbaum, F. Aujard. Physiological responses to chronic heat exposure in an aging non-human primate species, the gray mouse lemur (). Experimental Gerontology, 2011, 46 (9), pp.747. ⟨10.1016/j.exger.2011.05.007⟩. ⟨hal-00720176⟩