Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.

Jean-Yves Winum (1) , Fabrizio Carta (2) , C. Ward , P. Mullen (3) , D. Harrison (4) , Sp Langdon (3) , Alessandro Cecchi (2) , Andrea Scozzafava (2) , Ian Kunkler (5) , Claudiu T. Supuran (2)

1 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]
2 LCBI-UniFI - Laboratorio di Chimica Bioinorganica [UniFI, Firenze] = Laboratory of Bioinorganic Chemistry [UniFI Florence]
3 IGMM - Institute of Genetics and Molecular Medicine
4 University of St Andrews [Scotland]
5 Cancer Research UK Edinburgh Centre [Edinburgh, UK]

Domaines: Chimie organique

Jean-Yves Winum, Fabrizio Carta, C. Ward, P. Mullen, D. Harrison, et al.. Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.. Bioorganic and Medicinal Chemistry Letters, 2012, 22, pp.4681-4685. ⟨10.1016/j.bmcl.2012.05.083⟩. ⟨hal-00718717⟩