Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.

Marouan Rami (1) , A. Maresca , Fatma-Zohra Smaine (2) , Jean-Louis Montero (1) , Andrea Scozzafava (3) , Jean-Yves Winum (1) , Claudiu T. Supuran (3)

1 IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]
2 Laboratoire de Chimie Bioorganique
3 LCBI-UniFI - Laboratorio di Chimica Bioinorganica [UniFI, Firenze] = Laboratory of Bioinorganic Chemistry [UniFI Florence]

Domaines: Chimie organique

Marouan Rami, A. Maresca, Fatma-Zohra Smaine, Jean-Louis Montero, Andrea Scozzafava, et al.. Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.. Bioorganic and Medicinal Chemistry Letters, 2011, 21, pp.2975-2979. ⟨10.1016/j.bmcl.2011.03.055⟩. ⟨hal-00676372⟩