Identification of Heterogeneous Elastic Properties in Stenosed Arteries: a Numerical Plane Strain Study

Alexandre Franquet (1, 2, 3, 4) , Stéphane Avril (1, 2, 3, 4) , Pierre Badel (1, 2, 3, 4) , Rodolphe Le Riche (5, 3, 6)

1 CIS-ENSMSE - Centre Ingénierie et Santé
2 DB2M-ENSMSE - Département Biomécanique et Biomatériaux
3 LCG-ENSMSE - UMR 5146 - Laboratoire Claude Goux
4 IFRESIS - Institut Fédératif de Recherche en Sciences et Ingénierie de la Santé
5 CROCUS-ENSMSE - Equipe : Calcul de Risque, Optimisation et Calage par Utilisation de Simulateurs
6 DEMO-ENSMSE - Département Décision en Entreprise : Modélisation, Optimisation

Assessing the vulnerability of atherosclerotic plaques requires an accurate knowledge of the mechanical properties of the plaque constituents. It is possible to measure displacements in vivo inside a plaque using magnetic resonance imaging. An important issue is to solve the inverse problem that consists in estimating the elastic properties inside the plaque from measured displacements. This study focuses on the identifiability of elastic parameters e.g. on the compromise between identification time and identification accuracy. An idealised plane strain. Finite Element (FE) model is used. The effects of the FE mesh, of the a priori assumptions about the constituents, of the measurement resolution and of the data noise are numerically investigated.

Mots clés: Finite element; atherosclerosis; inverse method; identification; elasticity; artery

Domaines: Génie des procédés; Matériaux; Biomécanique [physics.med-ph]; Biomécanique [physics.med-ph]

Alexandre Franquet, Stéphane Avril, Pierre Badel, Rodolphe Le Riche. Identification of Heterogeneous Elastic Properties in Stenosed Arteries: a Numerical Plane Strain Study. Computer Methods in Biomechanics and Biomedical Engineering, 2012, 15 (12), pp.49-58. ⟨10.1080/10255842.2010.547192⟩. ⟨hal-00632399⟩