Tacrolimus versus cyclosporine as primary immunosuppression after heart transplantation: systematic review with meta-analyses and trial sequential analyses of randomised trials

Luit Penninga (1, 2) , Christian H. Møller (1, 3) , Finn Gustafsson (4) , Daniel A. Steinbrüchel (3) , Christian Gluud (1)

1 Copenhagen Trial Unit, Centre for Clinical Intervention Research, Cochrane Hepato-biliary Group, Department 3344
2 Department of Surgery and Transplantation C2122, Rigshospitalet
3 Department of Cardiothoracic Surgery RT 2152
4 Department of Cardiology, B2142

Mots clés: Heart transplantation; Cyclosporine; Tacrolimus; Calcineurin inhibitors; Meta-analysis

Luit Penninga, Christian H. Møller, Finn Gustafsson, Daniel A. Steinbrüchel, Christian Gluud. Tacrolimus versus cyclosporine as primary immunosuppression after heart transplantation: systematic review with meta-analyses and trial sequential analyses of randomised trials. European Journal of Clinical Pharmacology, 2010, 66 (12), pp.1177-1187. ⟨10.1007/s00228-010-0902-6⟩. ⟨hal-00627922⟩