Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs

Anja Frömberg (1) , Daniela Gutsch (1) , Daniel Schulze (1) , Claudia Vollbracht (2) , Gabriele Weiss (2) , Frank Czubayko (1) , Achim Aigner (1)

1 Institute of Pharmacology, Faculty of Medicine
2 Pascoe Pharmazeutische Präparate GmbH

Mots clés: Ascorbate; Dehydroascorbate; 5-FU; Paclitaxel; Prostate carcinoma

Anja Frömberg, Daniela Gutsch, Daniel Schulze, Claudia Vollbracht, Gabriele Weiss, et al.. Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs. Cancer Chemotherapy and Pharmacology, 2010, 67 (5), pp.1157-1166. ⟨10.1007/s00280-010-1418-6⟩. ⟨hal-00613924⟩