Comparative effects of various commercially available mouth-rinse formulations on oral malodour.

Saliha Saad (1)

1 Centre of Research in Biomedicine

Abstract Objectives: To compare a new mouthwash (SB12®) containing 0.025% chlorhexidine and 0.3% zinc for oral malodour reduction against four commercially available mouthwashes and negative control. A secondary aim was to compare the two methods for measuring volatile sulphur compounds (VSC) by halimetry and OralChroma. Methods: Organoleptic scale, halimeter and the OralChroma were used to assess oral malodour and VSC. The effects of five test formulations and water (negative control) were assessed after 30-, 60-, 90- and 180-minutes, with one week between the treatments to avoid any cross-over effect. Results: Reduction in H2S by halimetry and malodour levels by organoleptic assessment ranged from, slight (LacerFresh®) (P > 0.05), moderate (BreathRx®, SmartMouth®) (P < 0.01) to marked effect (SB12 ®, Listerine®) (P < 0.001) at all time points compared to water. The largest differences were observed at 30-minutes and decreased with time. SB12® showed separation from Listerine® at 180-minutes, using ANOVA plus Bonferroni's Multiple Comparison post-test (P < 0.05). Relationships between organoleptic, halimeter and OralChroma were between R2 = 0.795 to 0.926. Conclusion: SB12 shows a consistent and reproducible inhibitory effect on oral malodour parameters which in turn correlate well with each other.

Mots clés: Medicine

Saliha Saad. Comparative effects of various commercially available mouth-rinse formulations on oral malodour.. Oral Diseases, 2010, 17 (2), pp.180. ⟨10.1111/j.1601-0825.2010.01714.x⟩. ⟨hal-00599897⟩