Fluorescence study of tetracaine-cyclodextrin inclusion complexes

Emilia Iglesias-Martinez (1)

1 UDC - University of A Coruña

The steady state fluorescence emission from of the local anesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β-, and γ-cyclodextrin (CD) was investigated at various pH values. Emission was observed from the locally (LE) and the intramolecular charge transfer (ICT) excited states. The TCA:CD system found to be characterized by 1:1 associate in every case. The association constants of each complex were determined.

Mots clés: Physical Sciences

Emilia Iglesias-Martinez. Fluorescence study of tetracaine-cyclodextrin inclusion complexes. Supramolecular Chemistry, 2010, 22 (04), pp.228-236. ⟨10.1080/10610270903304400⟩. ⟨hal-00576631⟩