Adverse reactions to patent blue V dye - The New Start and Almanac experience

L. Barthelmes (1) , A. Goyal (1) , R.G. Newcombe (2) , F. Mcneill (3) , R.E. Mansel (1)

1 Department of Surgery
2 Department of Epidemiology
3 Department of Surgery

Blue dye with or without isotope has been widely used to identify the sentinel lymph node(s) in breast cancer. Patent blue V is used in the UK while its isomer isosulfan blue is used in the US. The allergic potential of isosulfan blue is well documented (1.4% adverse reactions) but that of patent blue V is less clearly defined.

Mots clés: anaphylaxis; allergy; breast cancer; sentinel lymph node biopsy; patent blue V; isosulfan blue

L. Barthelmes, A. Goyal, R.G. Newcombe, F. Mcneill, R.E. Mansel. Adverse reactions to patent blue V dye - The New Start and Almanac experience. EJSO - European Journal of Surgical Oncology, 2010, 36 (4), pp.399. ⟨10.1016/j.ejso.2009.10.007⟩. ⟨hal-00576172⟩