A European consensus report on blood cell identification: terminology utilized and morphological diagnosis concordance among 28 experts from 17 countries within the European LeukemiaNet network WP10, on behalf of the ELN Morphology Faculty.
Résumé
Lack of standardization of specimen processing procedures, staining, degree of skill in interpretation and terminology used still affects microscopic evaluation of peripheral blood and bone marrow cells. The new WHO classification, on the other hand, highlights the importance of morphological aspects for recognition of disease entities and better stratification of patients with myeloid neoplasms and, in particular, myelodysplastic syndromes (MDS). Within the activities of the WP10 of European LeukemiaNet Network, a Morphology Faculty of 28 expert morphologists from 17 European countries, initiated a project in February 2007 with the goal to increase the quality of diagnostics based on cytomorphology as the first technique worldwide and to support this by a web based consensus report, including a uniform nomenclature. Activities were mainly carried out via internet to find a final fully agreed cell name. In a final 2-day meting, cells without a full agreement were collectively reviewed and approved. At the end of the project 228 images with 604 labelled blood cells with the consensus name agreed by the EMF were available to be uploaded on the web for free consultancy.The appropriateness and the utility of the consensus method has been validated by an expert morphologist external to the EMF(JMB).
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PEER_stage2_10.1111%2Fj.1365-2141.2010.08366.x.pdf (272.72 Ko)
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