Perioperative Tumor Cell Dissemination In Patients With Primary Or Metastatic Colorectal Cancer

J.G. Tralhão (1, 2) , E. Hoti (3) , M. Serôdio (1) , P. Laranjeiro (4) , A. Paiva (4) , A.M. Abrantes (2) , M.L. Pais (4) , M.F. Botelho (2) , F. Castro Sousa (1)

1 Department of Surgery
2 Biophysics and Biomathematics Institute
3 Saint Vincents' University Hospital
4 Histocompatibility Centre of Coimbra

Although there is general correlation between TNM stage of colorectal cancer (CRC) and its prognosis, there is often significant variability of tumor behaviour and individual patient outcome, which is unaccounted for by pathologic factors alone. Our aim was to estimate the perioperative tumor cell dissemination in patients with primary or CRC liver metastases as a possible factor influencing the outcome.

Mots clés: Colorectal cancer; circulating tumor cells; flow cytometry detection

J.G. Tralhão, E. Hoti, M. Serôdio, P. Laranjeiro, A. Paiva, et al.. Perioperative Tumor Cell Dissemination In Patients With Primary Or Metastatic Colorectal Cancer. EJSO - European Journal of Surgical Oncology, 2010, 36 (2), pp.125. ⟨10.1016/j.ejso.2009.07.003⟩. ⟨hal-00557762⟩